Rerolls such as The D6, Rune of Perthro, or Soul of Isaac will generate Devil Room items.This works even if the boss does not normally drop items, such as Mom, Satan, or ?. Using the Satanic Bible changes the Boss Room's item pool to the Devil Room item pool for purposes other than direct boss rewards as well.

This does not affect the items dropped on The Void.Taking a deal in this form will not remove hearts, making the player able to get at least 2 Devil Room items for free on that floor. This also applies to the Lost form granted by the white fire on Downpour / Dross II.The Lost, Tainted Lost, and Tainted Jacob in his ghost form can safely take any Boss Room item pedestals and it has no effect on subsequent devil deals.On XL floors, both items will become Devil Deals, even if Satanic Bible was only used once.Bosses with set drops aside from Mom will still drop their normal item, but at the cost of one Heart Container.Collecting three items from this set will transform Isaac into Bookworm. This item belongs to the Bookworm set.This does not affect The Polaroid, The Negative, or Dad's Note.This item must be paid for with hearts and will prevent Angel Rooms from generating under most circumstances if taken, just like a normal Devil Deal. Once used, the boss for the floor will drop a Devil Deal instead of a Boss Room item.

Binding of isaac rebirth satan